Nuromol Pain Relief Tablets, Paracetamol and Ibuprofen, Pack Of 16, From The Makers Of Nurofen

Product Information

Nuromol is used for the temporary relief of mild to moderate pain, which has not been relieved by ibuprofen or paracetamol individually, such as migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, cold and flu symptoms, sore throat and fever in adults 18 years. Undesirable effects such as dizziness, drowsiness, fatigue and visual disturbances are possible after taking NSAIDs. The clinical studies that were provided to support the original marketing authorisation have confirmed that the reduced daily dose for paracetamol is effective.

The elderly have an increased frequency of adverse reactions to NSAIDs especially gastrointestinal bleeding and perforation which may be fatal (see Section 4. NSAIDS should be given with care to patients with a history of gastrointestinal disease (ulcerative colitis, Crohn's disease) as these conditions may be exacerbated (see section 4. When you want even more softness, Kleenex ultra soft tissues are there for you with a little extra TLC.Nuromol has a reduced dosage of paracetamol compared to solid dose oral paracetamol products that are already authorised with GSL classification and there is a lower rate of reported adverse events with the combination compared with the individual actives alone. Ibuprofen therefore elicits an analgesic effect through peripheral inhibition of the cycloxygenase-2 (COX-2) isoenzyme with a subsequent reduction in sensitisation of nociceptive nerve terminals. Consider oral administration of activated charcoal if the patient presents within 1 hour of ingestion of a potentially toxic amount.

Patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be managed in accordance with established guidelines. Patients appear to be at highest risk of these reactions early in the course of therapy, the onset of the reaction occurring in the majority of cases within the first month of treatment. The clinical efficacy of ibuprofen and paracetamol has been demonstrated in pain associated with headache, toothache and dysmenorrhoea, and fever, furthermore efficacy has been shown in patients with pain and fever associated with cold and influenza and in pain models such as sore throat, muscular pain or soft tissue injury and backache.Antiplatelet agents and selective serotonin reuptake inhibitors (SSRIs): Increased risk of gastrointestinal bleeding (see section 4. A randomised, double-blind placebo-controlled studies were conducted with the combination using the acute pain model of post-operative dental pain.

The administration of NSAIDs may cause a dose dependent reduction in prostaglandin formation and precipitate renal failure. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema and death.If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital.

Ibuprofen is well absorbed from the gastrointestinal tract and is extensively bound to plasma proteins. Ibuprofen, Paracetamol, Croscarmellose Sodium, Microcrystalline Cellulose, Colloidal Anhydrous Silica, Magnesium Stearate, Stearic Acid. Antihypertensives: (ACE inhibitors and Angiotensin II Antagonists) and diuretics: NSAIDs may reduce the effects of these drugs. Gastrointestinal (GI) bleeding, ulceration and perforation, which can be fatal, has been reported with all NSAIDs at any time during treatment, with or without warning symptoms or a previous history of serious GI events. While we have taken care in preparing this summary and believe it is accurate, it is not a substitute for your reading the product packaging and label prior to use.Since Nuromol is already classified as a Pharmacy Medicine, the MHRA considered the application against the General Sales criterion. Care is advised in the administration of Paracetamol to patients with severe renal or severe hepatic impairment. Management should be symptomatic and supportive and include the maintenance of a clear airway and monitoring of cardiac and vital signs until stable.